Hélène Tronchère Selected Research

phosphatidylinositol 5-phosphate

12/2013	A Shigella effector dampens inflammation by regulating epithelial release of danger signal ATP through production of the lipid mediator PtdIns5P.
1/2012	Phosphatase-dead myotubularin ameliorates X-linked centronuclear myopathy phenotypes in mice.
9/2011	Shigella flexneri infection generates the lipid PI5P to alter endocytosis and prevent termination of EGFR signaling.
9/2009	PtdIns5P protects Akt from dephosphorylation through PP2A inhibition.
3/2006	PtdIns5P activates the host cell PI3-kinase/Akt pathway during Shigella flexneri infection.

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Hélène Tronchère Research Topics

Disease

9	Congenital Structural Myopathies (Centronuclear Myopathy) 01/2016 - 02/2002
5	Infections 01/2016 - 03/2006
3	Inborn Genetic Diseases (Disease, Hereditary) 01/2016 - 07/2003
2	Bacillary Dysentery (Shigellosis) 02/2016 - 09/2009
2	Anaplastic Large-Cell Lymphoma (Ki 1 Lymphoma) 09/2011 - 09/2010
2	Neoplasms (Cancer) 09/2010 - 07/2003
2	Muscular Diseases (Myopathy) 11/2006 - 12/2003
1	Fibrosis (Cirrhosis) 01/2016
1	Inflammation (Inflammations) 12/2013
1	Disease Progression 01/2012
1	Dysentery 09/2011
1	Cadaver (Cadavers) 05/2011
1	Lymphoma (Lymphomas) 09/2010
1	Shock 02/2004
1	Oculocerebrorenal Syndrome (Lowe Syndrome) 07/2003
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 07/2003
1	Myotonic Dystrophy (Dystrophia Myotonica) 09/2002
1	Congenital, Hereditary, and Neonatal Diseases and Abnormalities (Congenital Disorders) 09/2002

Drug/Important Bio-Agent (IBA)

11	myotubularinIBA 01/2016 - 02/2002
5	phosphatidylinositol 5-phosphateIBA 12/2013 - 03/2006
5	Phosphoric Monoester Hydrolases (Phosphatases)IBA 01/2012 - 09/2002
4	Phosphatidylinositols (Phosphatidylinositol)IBA 01/2012 - 02/2004
3	LipidsIBA 12/2013 - 02/2004
3	phosphatidylinositol 3-phosphateIBA 01/2012 - 09/2002
2	Proteins (Proteins, Gene)FDA Link 01/2016 - 10/2013
2	Phosphoinositide PhosphatasesIBA 09/2011 - 05/2011
2	Anaplastic Lymphoma KinaseIBA 09/2011 - 09/2010
2	Phosphatidylinositol 3-Kinases (PI 3 Kinase)IBA 09/2009 - 03/2006
2	phosphatidylinositol 3,5-diphosphateIBA 11/2006 - 02/2004
1	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 02/2016
1	SeptinsIBA 01/2016
1	ConnexinsIBA 12/2013
1	Adenosine Triphosphate (ATP)IBA 12/2013
1	amphiphysinIBA 10/2013
1	NucleophosminIBA 09/2011
1	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 09/2011
1	Pyridinolcarbamate (P23)IBA 09/2011
1	Matrix Metalloproteinase 9 (Gelatinase B)IBA 09/2010
1	Heat-Shock Proteins (Heat-Shock Protein)IBA 09/2010
1	Matrix Metalloproteinases (MMPs)IBA 09/2010
1	Dynamin IIIBA 11/2006
1	Peptides (Polypeptides)IBA 12/2003
1	Phosphoprotein Phosphatases (Phosphatases, Protein)IBA 12/2003
1	PTEN Phosphohydrolase (PTEN Phosphatase)IBA 07/2003
1	TensinsIBA 07/2003
1	Messenger RNA (mRNA)IBA 09/2002